February 17, 2023
Reporter, Morning Rounds Writer
Good morning. We're pausing the newsletter on Monday in observance of Presidents Day, but we'll be back Tuesday.

politics

Health worker shortage grabs bipartisan attention from Senate committee

The shortage of doctors and nurses across the country is both an urgent problem and a source of common ground for the Senate’s health committee. Both Chairman Bernie Sanders (I-Vt.) and ranking member Bill Cassidy (R-La.) have listed health workforce problems as one of their top priorities — and yesterday Sanders said at a hearing he is already eyeing legislation to solve them. There’s also bipartisan consensus on expanding telehealth programs and increasing the mental health care workforce in particular.

But some fault lines are still wide: Sanders is plunging ahead on plans to interrogate pharmaceutical company executives on high drug costs, and Cassidy is pressing for probes into how the Biden administration has implemented a law he co-authored to end patients’ surprise medical bills. STAT’s Sarah Owermohle has more from the hearing.


health

Scientists link certain genes in women to cardiovascular risks from obesity

Scientists have connected hundreds of genes to obesity, but they’re still learning which ones matter for risks like heart disease or diabetes. A new study published yesterday in Nature Genetics turned up 91 genes linked to the accumulation of fat in the abdomen for women, compared to only 42 genes for men. That waist-to-hip ratio is considered a better measure of cardiovascular risk than BMI, so they zeroed in one gene in particular, called SNX10, that was most strongly associated with a high waist-to-hip ratio in women. 

The findings could potentially lead to tests to identify who is at the highest risk of cardiovascular problems, an appealing option when new, in-demand drugs for obesity have become available but at high cost. Developing a new drug to target the gene is another possibility, but not before understanding what metabolic ripples might follow blocking it. STAT’s Elaine Chen has more.


coronavirus

More Black and Hispanic Americans have long Covid symptoms, but fewer are diagnosed

Just as Black and Hispanic people in the U.S. have disproportionately borne the brunt of Covid-19 infections, so too are these Americans more likely to be burdened by long Covid — but not as often diagnosed as white people. These conclusions, based on health records, are among the first to emerge from the NIH’s RECOVER initiative, criticized last year as “a slow-moving glacier.” 

The first study, in the Journal of General Internal Medicine, found that Black and Hispanic patients were more likely to have more but different persistent symptoms. If hospitalized, they were more likely to have headaches, chest pain, and joint pain but less likely to have sleep disorders, cognitive problems, or fatigue. After milder infections, Black adults were more likely to have blood clots in their lungs, chest pain, joint pain, anemia, or be malnourished; Hispanic adults were more likely to have dementia, headaches, anemia, chest pain, and diabetes; and white adults were most likely to have brain fog and fatigue.

The second study, in BMC Medicine, found that most adults and children diagnosed with long Covid were white, female, non-Hispanic, and likely to live in areas with low poverty and greater access to health care.



Closer Look

Why aren't there better ways to treat cramps?

An illustration of a woman reclining with a hot water bottle on her abdomenMolly Ferguson for STAT

Month after month cramps disrupt the lives of many who menstruate, made more distressing when go-to NSAIDs like Midol, Motrin, and Aleve don’t work. It’s estimated that nearly one in 5 people with dysmenorrhea — painful periods with or without an underlying condition like endometriosis or uterine fibroids —  don’t get relief from existing treatments. And yet, there’s little funding for research into the problem, STAT contributor Calli McMurray reports. 

Studies of treatments that looked promising — even research on Viagra to treat menstrual pain — have fizzled, with few patients participating and not much grant funding. Having a better understanding of what’s causing the pain could help researchers develop more effective treatments. “There’s a whole raft of these newer treatments that we can test out if we just know who to use them on,” said OB-GYN Frank Tu of NorthShore University Health System. Read more about the challenges and possibilities.


addiction

Nonfatal drug overdoses are key predictors of later deaths, but data gathering is uneven

As the opioid epidemic continues to take more than 100,000 lives a year, a new letter to JAMA calls attention to nonfatal drug overdoses. These red flags can predict future deaths, but they are likely undercounted by states. To begin with, not all states comprehensively report drug overdoses, and those that do may not capture all of them. Most reports come from hospital emergency departments or first responders, as you’d expect, followed by community programs. But not everyone who has an overdose connects with medical services or community programs, the researchers say.

“State nonfatal overdose data can inform local communities about the dangers of the illicit drug supply and provide data-driven insights to inform the distribution of lifesaving overdose-reversing drugs (e.g., naloxone), harm reduction resources, and treatment services,” the authors write.


nutrition

Kids need to eat more fruit and veg, study says

Just when they need nutritious foods to grow and develop, a concerning proportion of kids ages 1 to 5 aren’t eating a fruit or vegetable every day. A new CDC survey that asked parents what their children ate in the previous week found that in 2021, almost a third didn’t eat a daily fruit and nearly half didn’t have a daily vegetable, but more than half had a sugar-sweetened drink at least once that week. 

The percentage of children who did not eat a daily fruit or vegetable was higher among those who were 2 to 5 years old, Black, or lived in households with limited food sufficiency. These children also were more likely to have sugary drinks. Rates varied by state: In Vermont, 30% of children didn’t eat a daily vegetable, compared with 64% in Louisiana. For sugar-sweetened drinks, rates ranged from 39% in Maine to 79% in Mississippi.


by the numbers

feb. 16 cases covid-chart-export - 2023-02-16T163639.993


feb. 16 deaths covid-chart-export - 2023-02-16T163707.810


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What we're reading

  • Sen. John Fetterman checks into hospital for 'clinical depression' treatment, his office says, CNBC
  • Steak dinners, sales reps, and risky procedures: Inside the big business of clogged arteries, ProPublica
  • Ginkgo chief Jason Kelly is chairing a federal biotech advisory group. Is that a conflict of interest? STAT
  • Where more people will die — and live — because of hotter temperatures, Washington Post
  • Here’s another sign the Biden administration is taking a harsher stance on hospital consolidation, STAT

Thanks for reading! Til Tuesday,


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